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Malaria Diagnsotics Issue

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News

WHO – Investing in Malaria Makes Sense

GENEVA — In marking World Malaria Day on April 25, the World Health Organization says investing in malaria control is good health policy and makes good economic sense. Great progress is being made in controlling malarial infection, and WHO officials think now is the time to capitalize on recent successes in the battle against this preventable and […]

Trial: Malaria Chemoprevention Protects Children

The non-governmental organization Doctors Without Borders, or Medecins Sans Frontieres, has launched a new, malaria prevention campaign in several countries in sub-Saharan Africa aimed at protecting the illnesses’ most vulnerable population – children under the age of five. During the campaigns at the height of malaria season – from July to October – young children […]

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Research

British Container Breeding Mosquitoes: The Impact of Urbanisation and Climate Change on Community Composition and Phenology

The proliferation of artificial container habitats in urban areas has benefitted urban adaptable mosquito species globally. In areas where mosquitoes transmit viruses and parasites, it can promote vector population productivity and fuel mosquito-borne disease outbreaks. In Britain, storage of water in garden water butts is increasing, potentially expanding mosquito larval habitats and influencing population dynamics […]

Wolbachia Infection Modifies the Profile, Shuttling and Structure of MicroRNAs in a Mosquito Cell Line

MicroRNAs (miRNAs) are small non-coding RNAs that play important roles in many biological processes such as development, cell signaling and immune response. Small RNA deep sequencing technology provided an opportunity for a thorough survey of the miRNA profile of a mosquito cell line from Aedes aegypti. We characterized the miRNA composition of the nucleus and […]

IgG1 and IgG4 Antibody Responses to the Anopheles gambiae Salivary Protein gSG6

Human antibody response to the Anopheles gambiae salivary protein gSG6 has recently emerged as a potentially useful tool for malaria epidemiological studies and for the evaluation of vector control interventions. However, the current understanding of the host immune response to mosquito salivary proteins and of the possible crosstalk with early response to Plasmodium parasites is […]

Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum

Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite utilized as a redox cofactor and enzyme substrate in numerous cellular processes. Elevated NAD+ levels have been observed in red blood cells infected with the malaria parasite Plasmodium falciparum, but little is known regarding how the parasite generates NAD+. Here, we employed a mass spectrometry-based metabolomic approach […]

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