Malaria Host Range

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QUESTION

What is a malaria host range?

ANSWER

Usually, a malaria host range refers to the natural geographical range of one of the hosts of a particular species of malaria. So, for example, Plasmodium reichenowi normally only infects chimpanzees. Chimpanzees live mainly in central and western Africa, so this would determine the host range for P. reichenowi. Other species of malaria, such as those that infect humans, have much larger host ranges, since humans live practically everywhere on the planet. In these cases, it is more likely that the range of that species of malaria is limited by climatic variables (malaria parasites require certain temperature ranges in which they are able to develop and mature) or the distribution of a suitable vector mosquito species, which also have climatic constraints.

Mosquitoes Transmission via Feces

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QUESTION

Can a mosquito give you malaria after having being on an infected person’s feces?

ANSWER

No. Malaria can only be transmitted via blood. As such, transmission via mosquitoes occurs when a mosquito feeds on the blood of an infected person, then bites someone who is not infected, and transfers the malaria parasite in the bite (this cannot happen straight away – the malaria parasite has to undergo some changes in the mosquito first).

Ingestion of Malaria Blood

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QUESTION

If someone were to eat/ingest the blood of an infected individual would they become infected with malaria? If an infected person’s blood was on their hands and they handled food, would eating the food put others at risk for malaria?

ANSWER

No, you would not get infected with malaria, as the malaria parasites must be transmitted into a person’s blood directly in order for them to be infected. As such, most transmission only occurs via mosquitoes: when a mosquito bites a person infected with malaria, it may pick up some of the malaria parasites while it feeds on the person’s blood. When it then goes to bite another person, after the parasite has replicated and changed inside the mosquito, it can pass the malaria on to the next person, again when it bites them and drinks the person’s blood.

Additionally, in some cases malaria can be transmitted by blood transfusion or organ donation, or from a mother to her unborn baby via the placenta, or through blood passed in childbirth. If you ate/drank malaria-infected blood, the parasites would be broken down and destroyed by your stomach acid.

Malaria in Summer

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QUESTION

Does malaria only occur during summer season?

ANSWER

That depends on where you are. The transmission of malaria depends on the presence of the mosquitoes which are required to transmit the disease (they do this when they bite you).

Many kinds of mosquito transmit malaria, though all are of the genus Anopheles. These different species have different climatic requirements, but all lay their eggs in pools of stagnant water, and the larve likewise live in this stagnant water until they develop into adults. As such, malaria is only transmitted when there are suitable pools of standing, stagnant water available for mosquitoes to breed, and also when the temperature is suitable for mosquito development (optimum temperature for mosquitoes is 25-27 degrees C—the malaria parasite develops most rapidly around this temperature as well, though can survive in temperatures about ten degrees cooler as well).

In some regions of the world, this combination of conditions is only met in the summer time, which means that malaria transmission only occurs during this season. In other parts of the world, such as coastal West Africa, conditions are suitable for mosquito breeding and malaria development all year round, which means that malaria transmission occurs throughout the year.

Is Malaria Contagious Between Humans?

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QUESTION

If someone has malaria, is it contagious?

ANSWER

No. Malaria cannot be transmitted via touching or saliva or air. In virtually all cases, it is only transmitted by the bite of an infected mosquito, and so cannot be passed from one person to another. There are a few exception—because the parasite lives in certain organs and in the blood, it can sometimes be transmitted via blood transfusion or organ transplant. It can also pass via the placenta from a mother to her unborn child, or to the child during childbirth.

Malaria: Mode of Transmission

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QUESTION

What is the mode of transmission of Malaria?

ANSWER

Malaria is transmitted normally via the bite of an infected mosquito. These mosquitoes, always female and of the genus Anopheles, carry malaria parasites in their salivary glands. The parasites, at this part of their life cycle known as sporozoites, are introduced into the host’s blood when the mosquito takes a blood meal. From there, the sporozoites travel to the liver, reproduce (this process may take several weeks), then finally re-enter the blood stream. At this point, the patient will begin to experience symptoms. Eventually, the malaria parasites change again, into gametocytes, which are picked up by another mosquito, again when it bites the infected person. In this way, the life cycle of the malaria parasite continues.

Because malaria reproduces in the blood and in the liver, in some cases malaria can be transferred via organ transplant or blood transfusion. In addition, malaria parasites can cross the placenta, and so can be transmitted from a mother to her unborn child, either in the womb or during childbirth. This is known as congenital malaria.

Discovery of Malaria

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QUESTION

Who was the discoverer of malaria?

ANSWER

Malaria has been known to humans since ancient times, though what exactly caused it and how it was transmitted was not known. The parasite which causes malaria, from the genus Plasmodium, was first observed in the blood of a patient who had died from the disease by Charles Louis Alphonse Laveran, a French physician working in Algeria. This was in 1880; a few years later, in 1897-1898, a British army doctor called Ronald Ross showed that malaria could be transmitted via the bite of a mosquito. Both doctors eventually received the Nobel Prize for their discoveries.

Causes of Malaria

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QUESTION

What are the causes of malaria?

ANSWER

Malaria is caused by a parasite called Plasmodium, which is transmitted via the bites of infected mosquitoes. In the human body, the parasites multiply in the liver, and then infect red blood cells. Usually, people get malaria by being bitten by an infective female Anopheles mosquito. 

Only Anopheles mosquitoes can transmit malaria and they must have been infected through a previous blood meal taken on an infected person. When a mosquito bites an infected person, a small amount of blood is taken in which contains microscopic malaria parasites. About 1 week later, when the mosquito takes its next blood meal, these parasites mix with the mosquito’s saliva and are injected into the person being bitten.

Because the malaria parasite is found in red blood cells of an infected person, malaria can also be transmitted through blood transfusion, organ transplant, or the shared use of needles or syringes contaminated with blood. Malaria may also be transmitted from a mother to her unborn infant before or during delivery (“congenital” malaria).

Malaria Transmission

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QUESTION

How is malaria transmitted?

ANSWER

Malaria is caused by a parasite called Plasmodium, which is transmitted via the bites of infected mosquitoes. In the human body, the parasites multiply in the liver, and then infect red blood cells. Usually, people get malaria by being bitten by an infective female Anopheles mosquito. 

Only Anopheles mosquitoes can transmit malaria and they must have been infected through a previous blood meal taken on an infected person. When a mosquito bites an infected person, a small amount of blood is taken in which contains microscopic malaria parasites. About 1 week later, when the mosquito takes its next blood meal, these parasites mix with the mosquito’s saliva and are injected into the person being bitten.

Because the malaria parasite is found in red blood cells of an infected person, malaria can also be transmitted through blood transfusion, organ transplant, or the shared use of needles or syringes contaminated with blood. Malaria may also be transmitted from a mother to her unborn infant before or during delivery (“congenital” malaria).

Malaria Effect on Host

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QUESTION

What is the effect of malaria on host?

ANSWER

In the human host, malaria can often make a person very sick, though the exact symptoms and severity of the disease depends on the type of malaria (five different kinds of malaria infect humans). Many people will have a high fever, chills, nausea and body aches. In a symptom very typical of malaria, a patient will experience cyclical fever, with periods of no fever in between, lasting between one and two days. In infections with Plasmodium falciparum, the most dangerous kind of malaria, patients may experience impaired consciousness, a sign of “cerebral malaria”, which can lead to loss of consciousness, coma and even death.

In terms of the mosquito host (more commonly called the vector), the insect does not experience “illness” in the same way as the human host, and the parasite does not seem to have a particularly negative effect on the mosquito. However, some research has shown that infection with malaria may cause a mosquito to seek out blood meals more frequently, which scientists argue is an adaptation of the malaria parasite to ensure that its life cycle is continued.