Transmission of Malaria from Person to Person

QUESTION

I was in Lagos, Nigeria and i was bitten. I had stomach ache and diarrhea for a day then back to normal. Just for precaution I checked my blood and the doc said that I have a mild malaria in my blood and he gave me a medicine. If i have malaria can I affect or transmit the malaria to other people like my friends or my wife by the saliva or by any means?

ANSWER

No, you cannot directly transmit malaria to other people. It can only be transmitted via the bite of an infected mosquito; as such, while you are recovering from malaria, you should take care not to be bitten by any mosquitoes, because if these mosquitoes then went on to bite someone else, they might get infected with malaria.

Since malaria infects the blood, if large amounts of blood are transferred between people, for example during a blood transfusion, organ transplant or during childbirth, then malaria can sometimes also be transmitted. But under normal circumstances, you can not directly transfer malaria to another person.

Treatment of recurrent Malaria

QUESTION

If one takes the first dose of Coartem and tests indicate presence of malaria parasites,is it advisable to take a second round of coartem, or to start on quinine? Is quinine usually administered on its own or in conjunction with another drug? At what point is malaria considered complicated?

ANSWER

Usually, if a first round of treatment is unsuccessful, a doctor will prescribe a different type of oral medication for another attempt, such as atovaquone-proguanil or doxycycline in combination with another anti-malarial.

Quinine, when administered orally, can be given alone but is more commonly given with another anti-malarial compound such as doxycycline, tetracycline or clindamycin.

In cases of complicated malaria, it is administered intravenously. There are a number of symptoms which, in combination with a history of high fever, define complicated/severe malaria, among which are:

  • Prostration (inability to sit), altered consciousness lethargy or coma
  • Breathing difficulties
  • Severe anaemia
  • Generalized convulsions/fits
  • Inability to drink/vomiting
  • Dark and/or limited production of urine

In addition, intravenous quinine may be given to patients who are unable to take oral medication for whatever reason.

Dormant Malaria

QUESTION

I was bitten by mosquitoes many years ago and I was wondering can the symptoms lie dormant for as long as 40 years? The reason I am asking is that every summer I am ill with several of these symptoms. I do not have a good immune system.

ANSWER

There are a couple of types of malaria, namely Plasmodium vivax and Plasmodium ovale, which can lie dormant for many years, and often cause relapses at regular intervals.

Next time you suffer from these symptoms, you should go to your doctor and have a blood test to check for malaria; while you are experiencing symptoms, if you have malaria, the parasites will be visible in your blood.

Once positively diagnosed, your doctor can provide you with treatment. If you do have malaria, you will need one medication to clear the infection from your blood (which kind depends on where you were when you got those mosquito bites; malaria has become resistant to certain types of medication in some areas), plus another type of medication to kill the dormant forms which are responsible for the yearly relapses. This latter medication is called primaquine, and is not recommended for people with G6DP deficiency, so you should be tested for this prior to taking the medication.

Having said all of that, it is very important to get the blood test if you suspect you have malaria, because the symptoms of malaria are very general (fever, chills, nausea, aches) and can be mistaken for many other illnesses. If your blood test is negative for malaria, then you should talk to your doctor about other possible infections.

Malaria and Weight Loss

QUESTION

Can malaria make you lose weight? Can malaria cause itching in the body.

ANSWER

Since malaria is often associated with extreme nausea and high fever, this can often cause people to lose their appetite and not eat properly while they are experiencing infection, leading to weight loss.

However malaria is usually quite an acute infection, lasting a few days to at most a few weeks (there are exceptions, whereby patients have been observed to be chronically infected for much longer periods of time, though they rarely experience frequent symptoms during these longer periods and as such would not be expected to lose weight), and so the period of time in which weight loss would occur is very short. Itching is not a symptoms commonly associated with malaria, though muscle aches and pains are common.

Massage Therapy and Malaria

QUESTION

What massage therapy has helped with malaria and what effects did it have on the patient?

ANSWER

As far as I am aware, massage therapy has never been shown to have any positive effects on malaria infection. If a patient has malaria, they must receive medical treatment, either in the form of oral tablets or if the disease has already progressed to a severe state, intravenous drugs.

Malaria Parasite

QUESTION

Which parasite transmits malaria?

ANSWER

Malaria is caused by a parasite called Plasmodium, which is transmitted via the bite of an infected mosquito. The parasite passes into the blood of the human patient when the mosquito bites, via its saliva. There are five species of Plasmodium which normally infect humans: P. falciparum, P. malariae, P. ovale, P. vivax and P. knowlesi. 

Malaria Statistics for Past Ten Years

What are the key statistics for global malaria over the past decade?

ANSWER
The World Health Organization’s World Malaria Report summarizes global malaria burden, including trends in mortality rates and economic impact. Here are selected figures from the 2011 report.

Estimated malaria cases, 2010

  • Globally: 216 million
  • Africa: 174 million
  • Americas: 1 million
  • Eastern Mediterranean: 10 million
  • Europe: 200
  • South-East Asia: 28 million
  • Western Pacific: 2 million

Estimated deaths from malaria, 2010

  • Globally: 655 000
  • Africa: 596 000
  • Americas: 1 000
  • Eastern Mediterranean: 15 000
  • Europe: 0
  • South-East Asia: 38 000
  • Western Pacific: 5 000

Figures on malaria deaths

  • 91% of deaths were in Africa
  • 86% of deaths were in children under 5 years of age

Population at risk

  • 3.3 billion (half of the world population)

Number of countries affected by malaria

  • 106

Six countries account for 60%, or 390,000, of malaria deaths

  • Nigeria
  • Democratic Republic of the Congo
  • Burkina Faso
  • Mozambique
  • Cote d’Ivoire
  • Mali

Malaria mortality rates have fallen since 2000

  • Globally: by more than 25%
  • Africa: by 33 %
  • Americas: by 55 %
  • Europe: by 99 %
  • Western Pacific: by 42 %
  • Between 2000 and 2010 out of 99 countries with ongoing malaria transmission 43 countries recorded decreases of more than 50% in the number of malaria cases
  • another 8 countries recorded decreases of more than 25%

Required health expenditure (Abuja declaration)

  • 15% of national budget

Economic cost

  • Direct: USD 12 billion per year in direct losses,
  • lost 1.3% of GDP growth per year for Africa.

Costs of interventions

  • Long-lasting insecticidal net that lasts three years: US$ 1.39 per person per year of protection
  • Course of artemisinin-based combination therapy (ACT) for an adult: US$ 0.90 – 1.40
  • Course of artemisinin-based combination therapy (ACT) for a young child: US$ 0.30 – 0.40
  • Rapid diagnostic test: US$ 0.50

Check out Roll Back Malaria for more information.

Malaria with Liver and Kidney Problems

QUESTION

Can someone please tell me what kind of malaria this is. What part of the body it attacks, e.g., cerebral? Patient presenting with liver and kidney “problems”. What could these be?

ANSWER

I am not sure I fully understand your question, but the type of malaria which is associated with cerebral malaria, and also tends to have the most adverse effects on other organs (such as the kidneys) is Plasmodium falciparum. However, all species of malaria go through the liver as part of their life cycle, so all may invoke some kidney problems. The four other types of malaria which infect humans are P. vivax, P. ovale, P. malariae and P.knowlesi.

Malaria in Myanmar (Burma)

QUESTION

Is Malaria an issue in Myanmar where I am going in June?

ANSWER from Malaria.com Editor

YES. Malaria is a risk in all rural areas of the country below 1,000 meters of altitude (anything below 3300 feet). Rangoon/Yangon and Mandalay do not have malaria.

You should take medication to prevent malaria (prophylaxis) throughout your stay, and also protect yourself from getting bitten by mosquitoes if you are travelling to risk areas for malaria. Personal protection measures including sleeping under an insecticide treated bednet, wearing insect repellent and wearing long-sleeved clothing, especially in the evenings, early morning and throughout the night, which is when the mosquitoes that transmit malaria are active and feeding.

Myanmar/Burma is known to have strains of malaria which are resistant to certain medications; specifically, chloroquine resistance is widespread, while some areas in addition have malaria which is resistant to mefloquine (sold as Lariam). As such, the CDC recommends atovaquone-proguanil (sold as Malarone) or doxycycline if you will be travelling in the provinces of Bago, Kachin, Kayah, Kayin, Shan, and Tanintharyi. In all other areas of the country, mefloquine should also be considered as an option.

Answer from Malaria.com medical advisor

For anyone planning a trip abroad its important to know the health risks in your destination. Malaria is an especially important concern for anyone traveling to tropical or subtropical regions. Here’s what I found on the CDC Travelers’ Health website. I find this is the best place to look for this information.

  • Areas of Burma with Malaria: Rural areas throughout the country at altitudes
  • If you will be visiting an area of Burma with malaria, you will need to discuss with your doctor the best ways for you to avoid getting sick with malaria. Ways to prevent malaria include the following:
  • Taking a prescription antimalarial drug.
  • Using insect repellent and wearing long pants and sleeves to prevent mosquito bites. Sleeping in air-conditioned or well-screened rooms or using bednets.
  • Some areas of Burma have resistance to certain antimalarial drugs.

See the malaria information for Burma to find out which antimalarial drug is appropriate for the area you plan to visit in Burma.