Malaria Detection

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QUESTION

what’s the newest form of malaria detection?

ANSWER

While the traditional form of malaria detection has been through microscopy of a blood film slide, two new technologies have recently emerged. The first is the use of reagent strips, which are impregnated with molecules that bind to various other proteins present in the blood during a malaria infection. These reagent strips are usually manufactured as part of a rapid diagnostic test (RDT) kit, whereby a patient only has to provide a single drop of blood, and the result can be read within minutes, a bit like a pregnancy test. The other new method which has emerged is based on PCR (polymerase chain reaction) technology. This method looks for malaria DNA directly in the patient’s blood, using specific sequences of DNA that are unique to the malaria parasite. This method is expensive and takes several hours at minimum, but is very sensitive, and even very low levels of malaria can be detected.

Malaria in Australia and Bali

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QUESTION

Is Australia, Bali or Tasmania in the malaria affected area?

ANSWER

While malaria used to be endemic in parts of Australia (not Tasmania—it is too cold), the country was declared to be free of malaria transmission in 1981. However, several hundred cases are reported in Australia every year, mainly brought back by travellers returning from other regions, such as south-east Asia and Africa.

The tropical northern region of Australia, i.e. Northern Queensland and particularly the Torres Strait area, is climatically very suitable for malaria transmission, and some local outbreaks may occur. Similarly, Bali is climatically very suitable for malaria, and some transmission does occur, though not high levels. For both Bali and northern Australia, it is not usually considered necessary to take anti-malarial medication while visiting the region, but precautions should be taken against getting mosquito bites, as this is how malaria is transmitted. Such precautions include sleeping under an insecticide-treated bednet, wearing long-sleeved clothing in the evenings and at night, and wearing insect repellent on exposed skin.

Malaria in Haiti

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QUESTION

I just recently returned from Senegal, 60 days ago, in which I had taken Malaria medicine; Chloroquine. I am heading to Haiti in 5 days, and wondering if I am in need of taking Malaria medicine again, or was the time frame close enough that it would be fine to go without.

ANSWER

You are only protected against malaria while you are taking the anti-malarial prophylactic medicine. All of Haiti is considered at risk for malaria, and so you should talke anti-malarial medication throughout the duration of your stay, plus the required time afterwards (depending on which type of prophylactic medication you take). Chloroquine is considered suitable as an anti-malarial for Haiti, as is atovaquone-proguanil (Malarone), doxycycline and mefloquine (Lariam).

Insecticide Treated Bednets (ITNs) Research

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QUESTION

I want to know about the treated bed net, because I want research about the ITNs. So please help me find some reasearch papers.

ANSWER

There are a wealth of scientific studies on ITNs. I will list a few here, which in turn will lead you to many others through their cited references. I am purposefully mostly mentioning papers published in open access journals, since many others restrict unsubscribed readers to only the abstract and not the full paper.

Fever and Body Aches with Malaria

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QUESTION

Is bad throat and fever with with body ache the symptom of malaria?

ANSWER

While fever and body aches are certainly some of the symptoms associated with malaria, a sore throat is well common, but could be the result of enlarged lymph nodes. It is important to note that these symptoms are also present with many other diseases; in fact, the symptoms of malaria are so general that sometimes it is difficult to diagnose, and a blood test should be performed to confirm that a patient is indeed suffering from malaria before treatment is given.

Tested Positive for Malaria

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QUESTION

I was found with malaria 0.25% positive in my test report….. will this make to reject my application from a Malaysian university?

ANSWER

Malaria is an infection with a parasite of the genus Plasmodium; all types are very treatable, and so even if you have tested positive, you can easily get medication which will allow you to recover fully from the disease. While some  universities require a health test, since malaria is completely treatable, a positive test for this disease should not stop you from being admitted to the university. However, you should get treated as soon as possible; ask your doctor what kind of medication is most appropriate for the type of malaria you have.

How many types of malaria are there?

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QUESTION

How many types of malaria are there?

ANSWER

There are four species of malaria parasite that commonly infect humans. These are: Plasmodium falciparum, P. vivax, P. ovale and P. malariae. In addition, a fifth species, P. knowlesi, is starting to draw public health attention as an infection in humans in south-east Asia, and particularly Borneo – previously, it was thought to only infect macaque monkeys.

Apart from these five species, there are many other species of Plasmodium, which infect other primates (including gorillas, chimpanzees and orangutans), rodents, birds and reptiles. A closely related group of parasites, called Hepatocystis, infects monkeys, squirrels, hippopotamus and bats.

Malaria in Africa

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QUESTION

What percent of Africa has malaria?

ANSWER

That is very difficult to measure, but maps of malaria transmission potential show that malaria is potentially present across most of the continent, excluding the heart of the Sahara and Kalahari deserts, and the highlands of Ethiopia, Lesotho and Uganda/Rwanda. Other parts of the continent, such as the coastline of North Africa (along the Mediterranean) and much of South Africa and Zimbabwe likely only experiences seasonal transmission of malaria, with some parts of the year too cold and/or dry to support transmission. The below map shows the distribution of malaria throughout Africa, and should give you some idea of the percentage landcover that is affected.

Distribution of endemic malaria

Distribution of endemic malaria in Africa. Picture courtesy of http://siteresources.worldbank.org/NEWS/Images/malaria-map.jpg

Treatment of Malaria in India

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QUESTION

In India how to treat a child and adult suffering from malaria?

ANSWER

Chloroquine-resistant malaria has been observed in India and so the first line drug of choice should be an artemisinin-derivative in combination with another drug (this group of medications are more generally known as “artemisinin-based combination therapies” or ACTs). A common example of this is artemether in combination with lumefantrine, which is marketed as Coartem. Coartem is also used to treat malaria in children over 11 pounds (5 kg) in weight.

Joint Pain and Malaria

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QUESTION

Could an onset of joint pain and swelling plus hurting all over be a residual for someone who has had malaria?

ANSWER

Once someone has been treated for malaria, they should not experience any further residual effects, particularly if the infection was uncomplicated and treated using oral medication. Joint pain, swelling and pain could well be indications of another infection, and so medical advice should be sought immediately.