Malaria Help from U.S. Nurses

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QUESTION

What can American nurses do to help those with malaria?

ANSWER

It is great that you are interested in helping the fight against malaria. One very valuable thing that nurses can do, given their crucial medical training, is volunteer overseas in places that are hard-hit by malaria. Websites such as this: Volunteer Abroad post these kinds of opportunities when they become available. Other, longer-term, volunteering opportunities are also available through governmental programs such as Peace Corps.

Closer to home, nurses can help to galvanize their communities to raise awareness about malaria. Another large-scale effort throughout the United States has been to try to raise money to buy long-lasting insecticide treated bednets for communities around the world, and particularly in sub-Saharan Africa, which are especially at risk of malaria. You could hold a fund-raising event in your community, or perhaps get involved with the initiatives in other ways. Many organizations are working towards bednet distribution, and links to just a couple of them are here:

Malaria No More

Project Mosquito Net

What is Malaria

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QUESTION

What is malaria?

ANSWER

Malaria is a serious and sometimes fatal disease caused by a parasite, of the genus Plasmodium, that commonly infects a certain type of mosquito (of the genus Anopheles) which feeds on humans. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. Four kinds of malaria parasites can infect humans: Plasmodium falciparum, P. vivax, P. ovale, P. knowlesi and P. malariae. Infection with P. falciparum, if not promptly treated, may lead to death. Although malaria can be a deadly disease, illness and death from malaria can usually be prevented.

Malaria Life Cycle

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QUESTION

What is the life cycle of malaria?

ANSWER

Malaria is caused by a single celled organism in the genus Plasmodium. Five species of Plasmodium infect humans, but all follow a very similar life cycle, including two separate cycles of asexual reproduction in the human host (one in the liver, called the exo-erythrocytic cycle, and one in the blood, and specifically inside red blood cells, known as the erythrocytic cycle) and a sexual reproductive stage inside the mosquito definitive host (usually called the “vector”). A schematic of the full life cycle is below, courtesy of the CDC (www.cdc.gov).

malaria life cycle CDC

Schematic of the malaria life cycle, courtesy of CDC (www.cdc.gov)

Scientific Name of Malaria

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QUESTION

what is the scientific name of malaria?

ANSWER

Malaria is caused by a single celled parasite of the genus Plasmodium. Five species infect humans, and their scientific names are Plasmodium falciparum (the most severe and deadly kind), P. vivax, P. ovale, P. malariae and P. knowlesi.

Malaria Parasite Classification

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QUESTION

What is the classification of malaria?

ANSWER

Malaria is caused by a single celled protist of the genus Plasmodium. This genus is part of a Phylum of single-celled protist organisms called Apicomplexa.

The Apicomplexans mostly posses an organ called an apicoplast, which is part of an apical structure designed to aid entry into a host cell. The Apicomplexa is split into two Classes, of which Plasmodium belongs to the Aconoidasida (lacking a structure called a conoid, which is like a set of microtubules), and then to the Order Haemosporidia, which contains parasites which invade red blood cells. Within this Order, Plasmodium belongs to the Family Plasmodiidae, which all share numerous characteristics, including asexual reproduction in a vertebrate host and sexual reproduction in a definitive host (a mosquito, in the case of the Plasmodium species that infect all mammals, including humans).

In the case of human malarias, the definitive host is often referred to as the vector. The family contains about twelve genera, of which one is Plasmodium, which itself is now often divided up into numerous sub-genera, and then again into hundreds of different species, of which five infect humans (P. falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi).

Malaria Effect on Host

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QUESTION

What is the effect of malaria on host?

ANSWER

In the human host, malaria can often make a person very sick, though the exact symptoms and severity of the disease depends on the type of malaria (five different kinds of malaria infect humans). Many people will have a high fever, chills, nausea and body aches. In a symptom very typical of malaria, a patient will experience cyclical fever, with periods of no fever in between, lasting between one and two days. In infections with Plasmodium falciparum, the most dangerous kind of malaria, patients may experience impaired consciousness, a sign of “cerebral malaria”, which can lead to loss of consciousness, coma and even death.

In terms of the mosquito host (more commonly called the vector), the insect does not experience “illness” in the same way as the human host, and the parasite does not seem to have a particularly negative effect on the mosquito. However, some research has shown that infection with malaria may cause a mosquito to seek out blood meals more frequently, which scientists argue is an adaptation of the malaria parasite to ensure that its life cycle is continued.

Which Malaria is Most Deadly

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QUESTION

In which form of malaria is the death rate highest?

ANSWER

The most dangerous form of malaria in people is Plasmodium falciparum. It causes the most severe symptoms (for example, “cerebral malaria”) and also the most deaths. It is widespread around the world, but most deaths due to P. falciparum (and in fact, all malaria) occur in sub-Saharan Africa.

Malaria Mosquito Classification

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QUESTION

What is the classification of mosquito that cause malaria?

ANSWER

The mosquitoes that cause malaria in humans (and indeed also in all other mammals) all belong to the genus Anopheles. They belong to the family Culicidae, which also includes other disease vectors such as Culex and Aedes, which transmit other diseases such as dengue virus, lymphatic filariasis, West Nile virus and Japanese encephalitis, among many others. The Culicidae are part of the Diptera, or the “true flies” which possess a pair of wings and a pair of halteres. The Diptera are part of the class Insecta, which is found within the phylum Arthropoda, in the Kingdom Animalia.

Can’t Get Rid of Malaria

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QUESTION

Each and every month I am suffering from malaria ..Treatment is also going on but I am unable to get rid of it.

ANSWER

It is very unusual to be reinfected so constantly with malaria. First of all, how are you getting diagnosed? You should be getting a blood test, and not relying on symptoms only; the symptoms of malaria are very general and it could be that you are suffering from something else entirely. The two main methods for accurate diagnosis are blood smear and rapid diagnostic test. The blood smear is used throughout the world, but can sometimes miss light infections (though if you feel sick, your infection is likely heavy enough to be detected by this method). The problem is that it requires a trained technician to take the sample, prepare it properly, and read it thoroughly and accurately. In my experience, many clinics, especially if they are rushed and busy, will not take the time to read a blood slide properly, and will just diagnose malaria without looking. This is really bad! It is very important to be properly diagnosed, so you can get the correct treatment, and if you don’t have malaria, you can be diagnosed for something else. The second kind of diagnostic is a rapid diagnostic test, or RDT. This looks for antibodies to malaria in your blood, and is very sensitive and quick. In an ideal world, you should try to have both done, to cross-check the results.

The next thing is to check whether you are receiving the correct treatment for the type of malaria that you have (if you are positively diagnosed with malaria). In many parts of the world, malaria has become resistant to some of the main medications used against it. Notably, this is the case in many places with Plasmodium falciparum, the most dangerous kind of malaria, which has become resistant to chloroquine in many parts of the world, to sulfadoxine-pyrimethamine (sold as Fansidar in many places) and also to mefloquine (sold as Lariam) in some places. As such, the World Health Organisation NEVER recommends these treatments be given as first line drugs against P. falciparum malaria – instead, they recommend artemisinin-combination therapies (ACTs), such as Alu, Coartem or Duo-Cotecxin. If you have been diagnosed with P. falciparum, you must try to take these kinds of drugs first. No resistance to ACTs has been reported, so if you take the full dose correctly, as prescribed by your doctor (and check to make sure the drugs are not expired), then you should be cured of malaria.

However, treatment does not stop you from getting infected again, and this is where prevention comes it. Preventing malaria is a cornerstone of control efforts. Since malaria is transmitted by a mosquito, preventing mosquitoes from entering the house, and particularly stopping them from biting you at night, is crucial. Screening all doors and windows can help stop mosquitoes from getting in, and in high transmission areas, many people will also spray inside their houses every once in a while with insecticides to kill any lingering insects. In addition, sleeping under a long-lasting insecticide treated bednet can drastically reduce the number of mosquitoes that are able to bite you at night. If you already have a net, it may be worth re-dipping it in insecticide (usually permethrin) to make sure it is still working effectively. The mosquitoes that transmit malaria feed at night, so if you are walking around outside in the evenings or at night, it is important to try to wear long-sleeved clothing, to prevent them from accessing your skin. All of these efforts will help prevent you from getting malaria again in the future.

What is Malaria?

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QUESTION

What is malaria?

What is the parasite that causes malaria?

ANSWER

Malaria is a serious and sometimes fatal disease caused by a parasite, of the genus Plasmodium, that commonly infects a certain type of mosquito (of the genus Anopheles) which feeds on humans. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. Four kinds of malaria parasites can infect humans: Plasmodium falciparum, P. vivax, P. ovale, P. knowlesi and P. malariae. Infection with P. falciparum, if not promptly treated, may lead to death. Although malaria can be a deadly disease, illness and death from malaria can usually be prevented.